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A 50% symptom improvement from baseline roughly equates to a Clinical Global Impression-Schizophrenia [43] scale score of much improved thus, is clinically meaningful [44]

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Structurally, they contain a basic scaffold of two or more phenylpropanoid units and the monomers forming lignans are cinnamic acid, propenyl benzene, allyl benzene and cinnamyl alcohol

Another mitochondria-targeting drug, dithiol a-lipoic acid, demonstrated renoprotective benefits in an animal model of hypertension and renal illness